Effectiveness of nursing educational interventions to improve adherence to cervical cancer screening and HPV testing in women of reproductive age

Authors

DOI:

https://doi.org/10.70577/asce.v5i2.933

Keywords:

cervical cancer; screening; HPV testing; nursing education; adherence; systematic review.

Abstract

Cervical cancer remains a major public health problem, particularly in settings where access barriers, misinformation, and low adherence to preventive screening persist. The objective of this systematic review was to analyze the effectiveness of nursing educational interventions in improving adherence to cervical cancer screening and HPV testing among women of reproductive age. A systematic review was conducted following the PRISMA 2020 guidelines. The search was performed in PubMed/MEDLINE, Scopus, Web of Science, SciELO, LILACS, and Google Scholar, including studies published between 2019 and 2026. After applying the inclusion and exclusion criteria, 25 scientific articles were selected for qualitative synthesis. The findings showed that educational interventions led or supported by nursing professionals increased knowledge about cervical cancer, HPV, and screening methods. They also improved risk perception, reduced perceived barriers, and increased women’s intention to undergo preventive testing. The most effective strategies were those that combined health education with individualized counseling, reminders, telephone follow-up, digital messages, home visits, and community-based support. It is concluded that nursing educational interventions are effective in improving adherence to cervical cancer screening and HPV testing, especially when they are sustained, culturally adapted, and integrated with accessible primary health care services.

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References

Abera, G. B., Abebe, S. M., & Worku, A. G. (2022). Impact of health education intervention on demand of women for cervical cancer screening: A cluster-randomized controlled trial. Trials, 23, 834. https://doi.org/10.1186/s13063-022-06765-0

Abu, S. H., Woldehanna, B. T., Nida, E. T., Tilahun, A. W., Gebremariam, M. Y., & Sisay, M. M. (2020). The role of health education on cervical cancer screening uptake at selected health centers in Addis Ababa. PLOS ONE, 15(10), e0239580. https://doi.org/10.1371/journal.pone.0239580

Agide, F. D., Sadeghi, R., Garmaroudi, G., & Tigabu, B. M. (2018). A systematic review of the effectiveness of health education interventions to increase cervical cancer screening uptake. European Journal of Public Health, 28(6), 1156–1162. https://doi.org/10.1093/eurpub/cky197

Akinola, A., & Constance, M. S. (2021). Impact of educational intervention on cervical cancer screening uptake among reproductive age women. International Journal of Community Medicine and Public Health, 8(4), 2053–2060. https://doi.org/10.18203/2394-6040.ijcmph20211280

Akintola, A., Dareng, E. O., Adebamowo, S. N., ACCME Research Group as part of the H3Africa Consortium, & Adebamowo, C. A. (2026). Impact of educational intervention on the uptake of self-sampling for HPV test-based cervical cancer screening. Frontiers in Oncology, 16, 1810950. https://doi.org/10.3389/fonc.2026.1810950

Al-Oseely, S., Abdul Manaf, R., & Ismail, S. (2025). Effectiveness of educational intervention on cervical cancer screening knowledge, attitude, and practice among Yemeni immigrant women in Klang Valley, Malaysia: A randomized controlled trial. Trials, 26, 466. https://doi.org/10.1186/s13063-025-08832-8

Ayanto, S. Y., Belachew, T., & Wordofa, M. A. (2024). Effectiveness of couple education and counseling on uptake of cervical cancer screening among women in Southern Ethiopia: A cluster randomized trial. Scientific Reports, 14, 12557. https://doi.org/10.1038/s41598-024-61988-2

Aydin, M., & Aydin Avci, İ. (2025). The effect of the music-supported education program on the awareness and health beliefs of Roma women about cervical cancer and screening. BMC Public Health, 25, 1536. https://doi.org/10.1186/s12889-025-21884-4

Bonuck, K. J., Angier, H., McCrimmon, S., Holderness, H., Erroba, J., Huguet, N., DeVoe, J. E., & Carney, P. A. (2023). A scoping literature review on evidence-based strategies to increase cervical cancer screening. Journal of Primary Care & Community Health, 14, 21501319231220994. https://doi.org/10.1177/21501319231220994

Choi, J. H., Park, S. J., & Park, S. Y. (2025). Systematic review of the effectiveness of cervical cancer prevention education interventions. European Journal of Gynaecological Oncology, 46(9), 17–25. https://doi.org/10.22514/ejgo.2025.116

Drokow, E. K., Effah, C. Y., Agboyibor, C., Sasu, E., Amponsem-Boateng, C., Akpabla, G. S., Ahmed, H. A. W., & Sun, K. (2021). The impact of video-based educational interventions on cervical cancer, Pap smear and HPV vaccines. Frontiers in Public Health, 9, 681319. https://doi.org/10.3389/fpubh.2021.681319

Ebu, N. I., Amissah-Essel, S., Asiedu, C., Akaba, S., & Pereko, K. A. (2019). Impact of health education intervention on knowledge and perception of cervical cancer and screening for women in Ghana. BMC Public Health, 19, 1505. https://doi.org/10.1186/s12889-019-7867-x

George, T. J., & Batra, K. (2022). Effect of a community-based multicomponent intervention on cervical cancer behavior among women: A randomized controlled trial. Journal of Education and Health Promotion, 11, 329. https://doi.org/10.4103/jehp.jehp_1742_21

Hosseini, Z., Mohseni, S., Momeni, R., Aghamolaei, T., Alavi, A., & Dadipoor, S. (2022). Increasing cervical cancer screening in Iran: Effectiveness of a theory-based educational intervention. Reproductive Health, 19, 186. https://doi.org/10.1186/s12978-022-01489-5

Khoshnazar, M. S., Tarrahi, M. J., & Shahnazi, H. (2024). Impact of virtual education based on health belief model on cervical cancer screening behavior in middle-aged women: A quasi-experimental study. Cancer Reports, 7(4), e2058. https://doi.org/10.1002/cnr2.2058

Koç, Z., Kurtoğlu Özdeş, E., Topatan, S., Çınarlı, T., Şener, A., Danacı, E., & Palazoğlu, C. A. (2019). The impact of education about cervical cancer and human papillomavirus on women’s healthy lifestyle behaviors and beliefs: Using the PRECEDE educational model. Cancer Nursing, 42(2), 106–118. https://doi.org/10.1097/NCC.0000000000000570

Kurt, G., & Akyuz, A. (2019). Evaluating the effectiveness of interventions on increasing participation in cervical cancer screening. The Journal of Nursing Research, 27(5), e40. https://doi.org/10.1097/JNR.0000000000000317

Linde, D. S., Andersen, M. S., Mwaiselage, J. D., Manongi, R., Kjaer, S. K., & Rasch, V. (2020). Effectiveness of one-way text messaging on attendance to follow-up cervical cancer screening among human papillomavirus–positive Tanzanian women (Connected2Care): Parallel-group randomized controlled trial. Journal of Medical Internet Research, 22(4), e15863. https://doi.org/10.2196/15863

Mili, M. A., Hossain, M. J., Poli, M. A., Kumar, S. B., Bhowmick, B., & Kundu, L. R. (2025). Impact of health education on knowledge and perception of cervical cancer and screening among rural women in Bangladesh. Scientific Reports, 15, 36812. https://doi.org/10.1038/s41598-025-20676-5

Mohammad, Z., Ahmad, N., & Baharom, A. (2022). The effects of theory-based educational intervention and WhatsApp follow-up on Papanicolaou smear uptake among postnatal women in Malaysia: Randomized controlled trial. JMIR mHealth and uHealth, 10(6), e32089. https://doi.org/10.2196/32089

Onyango, O. E., Masinde, D., & Ouma, C. (2024). Improving cervical cancer screening rates among women of reproductive age in rural Kisumu County through dialogue-based community health education. ecancermedicalscience, 18, 1713. https://doi.org/10.3332/ecancer.2024.1713

Page, M. J., McKenzie, J. E., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., Shamseer, L., Tetzlaff, J. M., Akl, E. A., Brennan, S. E., Chou, R., Glanville, J., Grimshaw, J. M., Hróbjartsson, A., Lalu, M. M., Li, T., Loder, E. W., Mayo-Wilson, E., McDonald, S., ... Moher, D. (2021). The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. BMJ, 372, n71. https://doi.org/10.1136/bmj.n71

Pan American Health Organization. (2026). Accelerating the elimination of cervical cancer: Cross-sectional examination of cancer prevention and control in Latin America and the Caribbean. https://www.paho.org/en/documents/accelerating-elimination-cervical-cancer-cross-sectional-examination-cancer-prevention

Romli, R., Shahabudin, S., Saddki, N., & Mokhtar, N. (2020). Effectiveness of a health education program to improve knowledge and attitude towards cervical cancer and Pap smear: A controlled community trial in Malaysia. Asian Pacific Journal of Cancer Prevention, 21(3), 853–859. https://doi.org/10.31557/APJCP.2020.21.3.853

Saei Ghare Naz, M., Kariman, N., Ebadi, A., Ozgoli, G., Ghasemi, V., & Rashidi Fakari, F. (2018). Educational interventions for cervical cancer screening behavior of women: A systematic review. Asian Pacific Journal of Cancer Prevention, 19(4), 875–884. https://doi.org/10.22034/APJCP.2018.19.4.875

Samami, E., Seyedi-Andi, S. J., Bayat, B., Shojaeizadeh, D., & Tori, N. A. (2021). The effect of educational intervention based on the health belief model on knowledge, attitude, and function of women about Pap smear test at Iranian health centers: A randomized controlled clinical trial. Journal of Education and Health Promotion, 10, 22. https://doi.org/10.4103/jehp.jehp_33_20

Sapkota, A., Adhikari, C., Kaphle, H. P., & Bist, B. B. (2026). Effectiveness of health education interventions for cervical cancer screening: A quasi-experimental study in Pokhara Metropolitan Slum, Nepal. PLOS Global Public Health, 6(1), e0005853. https://doi.org/10.1371/journal.pgph.0005853

Seyrafi, N., Homayuni, A., Hosseini, Z., Aghamolaei, T., Ghanbarnejad, A., & Mouseli, A. (2022). Effectiveness of educational intervention on women’s participation to cervical cancer screening: A quasi-experimental study based on PEN-3 model. BMC Cancer, 22, 1226. https://doi.org/10.1186/s12885-022-10331-x

Shrestha, A. D., Gyawali, B., Shrestha, A., Shrestha, S., Neupane, D., Ghimire, S., & Kallestrup, P. (2022). Effect of a female community health volunteer-delivered intervention to increase cervical cancer screening uptake in Nepal: A cluster randomized controlled trial. Preventive Medicine Reports, 29, 101948. https://doi.org/10.1016/j.pmedr.2022.101948

Weschasat, T., Wetchasat, N., & Chuemchit, M. (2024). The edutainment program on knowledge, perception, and uptake of cervical cancer screening among Muslim women in Southern Thailand: A quasi experimental study. BMC Public Health, 24, 1803. https://doi.org/10.1186/s12889-024-19287-y

Wong, C. L., Choi, K. C., Law, B. M. H., Chan, D. N. S., & So, W. K. W. (2019). Effects of a community health worker-led multimedia intervention on the uptake of cervical cancer screening among South Asian women: A pilot randomized controlled trial. International Journal of Environmental Research and Public Health, 16(17), 3072. https://doi.org/10.3390/ijerph16173072

World Health Organization. (2025). Cervical cancer. https://www.who.int/news-room/fact-sheets/detail/cervical-cancer

Published

2026-06-17

How to Cite

Cumbal Usiña , S. J., & Chapi Chandi , M. M. (2026). Effectiveness of nursing educational interventions to improve adherence to cervical cancer screening and HPV testing in women of reproductive age. ANNALS SCIENTIFIC EVOLUTION, 5(2), 3306–3335. https://doi.org/10.70577/asce.v5i2.933

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