Barriers and factors associated with cervical cancer screening and early diagnosis in women from rural areas: a systematic review

Authors

DOI:

https://doi.org/10.70577/asce.v5i3.1102

Keywords:

Cancer, Disease detection, Health education, Preventive medicine, Rural women

Abstract

Cervical cancer represents a significant public health issue, despite the availability of effective prevention and early detection measures; however, women living in rural areas face challenges that limit their access to screening programs, thereby increasing the risk of late diagnosis and reducing the likelihood of timely treatment. Therefore, the objective was to identify, analyze, and synthesize available evidence regarding the barriers and factors associated with access to screening and early diagnosis of cervical cancer among women living in rural areas. A systematic review was conducted based on the PRISMA 2020 guidelines; the search covered studies published between 2014 and 2025, and quantitative, qualitative, and mixed-methods studies related to access to screening and early diagnosis were selected. The findings revealed that the main barriers were a lack of knowledge about the disease, distance to health services, financial constraints, and fear of the diagnosis; cultural, educational, and institutional factors also played a role. Key factors facilitating participation included community health education, local availability of tests, support from community health workers, and the fact that the exams were free of charge. Rurality remains a determinant of health inequity; the identified barriers act in concert and increase the risk of late diagnosis. Community education, the strengthening of primary care, and the implementation of strategies tailored to local characteristics are fundamental actions for improving access to screening and promoting more timely care.

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References

Abdi, Y. H., Abdi, M. S., Bashir, S. G., Ahmed, N. I., & Abdullahi, Y. B. (2025). Understanding Global Health Inequality and Inequity: Causes, Consequences, and the Path Toward Justice in Healthcare. Public Health Challenges, 4(4), e70156. https://doi.org/10.1002/puh2.70156

Aleezada, Z. N., Patel, I., & Yusuf, N. (2025). Understanding HPV-Induced Cancers and Investigating the Barriers Faced by Low- and Middle-Income Countries in Prevention and Treatment. International Journal of Molecular Sciences, 26(12), 5581. https://doi.org/10.3390/ijms26125581

Aragie, H., Negash, H. K., Getnet, M., Tesfaye, W., Gela, Y. Y., Asefa, T., Woldeyes, M. M., & Endale, H. T. (2025). Barriers to healthcare access: A multilevel analysis of individual- and community-level factors affecting female youths’ access to healthcare services in Senegal. BMC Health Services Research, 25(1), 607. https://doi.org/10.1186/s12913-025-12761-2

Bezak, E., Carson-Chahhoud, K. V., Marcu, L. G., Stoeva, M., Lhotska, L., Barabino, G. A., Ibrahim, F., Kaldoudi, E., Lim, S., Marques Da Silva, A. M., Tan, P. H., Tsapaki, V., & Frize, M. (2022). The Biggest Challenges Resulting from the COVID-19 Pandemic on Gender-Related Work from Home in Biomedical Fields—World-Wide Qualitative Survey Analysis. International Journal of Environmental Research and Public Health, 19(5), 3109. https://doi.org/10.3390/ijerph19053109

Dombola, G. M., Manda, W. C., & Chipeta, E. (2021). Factors influencing contraceptive decision making and use among young adolescents in urban Lilongwe, Malawi: A qualitative study. Reproductive Health, 18(1), 209. https://doi.org/10.1186/s12978-021-01259-9

El-Zein, M., & Franco, E. L. (2025). Evolution and future of cervical cancer screening: From cytology to primary HPV testing and the impact of vaccination. Expert Review of Molecular Diagnostics, 25(5), 157-164. https://doi.org/10.1080/14737159.2025.2486653

Fang, J., Cheng, Y., Liu, Y., & Yang, Q. (2025). How delays in seeking medical care for cervical cancer patients are affected by their health-seeking behaviour: A qualitative study. BMC Public Health, 25(1), 2881. https://doi.org/10.1186/s12889-025-23783-0

Goldstein, A., Gersh, M., Skovronsky, G., & Moss, C. (2024). The Future of Cervical Cancer Screening. International Journal of Women’s Health, Volume 16, 1715-1731. https://doi.org/10.2147/IJWH.S474571

Kakotkin, V. V., Semina, E. V., Zadorkina, T. G., & Agapov, M. A. (2023). Prevention Strategies and Early Diagnosis of Cervical Cancer: Current State and Prospects. Diagnostics, 13(4), 610. https://doi.org/10.3390/diagnostics13040610

Malakoane, B., Heunis, J. C., Chikobvu, P., Kigozi, N. G., & Kruger, W. H. (2020). Public health system challenges in the Free State, South Africa: A situation appraisal to inform health system strengthening. BMC Health Services Research, 20(1), 58. https://doi.org/10.1186/s12913-019-4862-y

Murphy, J., Vallières, F., Bentall, R. P., Shevlin, M., McBride, O., Hartman, T. K., McKay, R., Bennett, K., Mason, L., Gibson-Miller, J., Levita, L., Martinez, A. P., Stocks, T. V. A., Karatzias, T., & Hyland, P. (2021). Psychological characteristics associated with COVID-19 vaccine hesitancy and resistance in Ireland and the United Kingdom. Nature Communications, 12(1), 29. https://doi.org/10.1038/s41467-020-20226-9

Omotoso, O., Teibo, J. O., Atiba, F. A., Oladimeji, T., Paimo, O. K., Ataya, F. S., Batiha, G. E.-S., & Alexiou, A. (2023). Addressing cancer care inequities in sub-Saharan Africa: Current challenges and proposed solutions. International Journal for Equity in Health, 22(1), 189. https://doi.org/10.1186/s12939-023-01962-y

Petersen, Z., Jaca, A., Ginindza, T. G., Maseko, G., Takatshana, S., Ndlovu, P., Zondi, N., Zungu, N., Varghese, C., Hunting, G., Parham, G., Simelela, P., & Moyo, S. (2022). Barriers to uptake of cervical cancer screening services in low-and-middle-income countries: A systematic review. BMC Women’s Health, 22(1), 486. https://doi.org/10.1186/s12905-022-02043-y

Phillips, M. J. (2023). Towards a social constructionist, criticalist, Foucauldian-informed qualitative research approach: Opportunities and challenges. SN Social Sciences, 3(10), 175. https://doi.org/10.1007/s43545-023-00774-9

Prieto-Egido, I., Guerrero-Curieses, A., Martínez-Fernández, A., & Rojo-Álvarez, J. L. (2026). Identifying high-risk pregnancies in rural areas with machine-manifold learning. Engineering Applications of Artificial Intelligence, 163, 112852. https://doi.org/10.1016/j.engappai.2025.112852

Ramos, M. D. (2026). The Theory of Planned Behavior (TPB), Self-Determination Theory (SDT), and Health-Seeking Behavior. En P. Liamputtong (Ed.), Handbook of Concepts in Health, Health Behavior and Environmental Health (pp. 567-591). Springer Nature Singapore. https://doi.org/10.1007/978-981-97-2085-9_27

Reynolds, S. S., Woltz, P., Keating, E., Neff, J., Elliott, J., Hatch, D., Yang, Q., & Granger, B. B. (2021). Results of the CHlorhexidine Gluconate Bathing implementation intervention to improve evidence-based nursing practices for prevention of central line associated bloodstream infections Study (CHanGing BathS): A stepped wedge cluster randomized trial. Implementation Science, 16(1), 45. https://doi.org/10.1186/s13012-021-01112-4

Srinath, A., Van Merode, F., Rao, S. V., & Pavlova, M. (2023). Barriers to cervical cancer and breast cancer screening uptake in low- and middle-income countries: A systematic review. Health Policy and Planning, 38(4), 509-527. https://doi.org/10.1093/heapol/czac104

Sutton, M. Y., Anachebe, N. F., Lee, R., & Skanes, H. (2021). Racial and Ethnic Disparities in Reproductive Health Services and Outcomes, 2020. Obstetrics & Gynecology, 137(2), 225-233. https://doi.org/10.1097/AOG.0000000000004224

Vázquez, E., Juturu, P., Burroughs, M., McMullin, J., & Cheney, A. M. (2024). Continuum of Trauma: Fear and Mistrust of Institutions in Communities of Color During the COVID-19 Pandemic. Culture, Medicine, and Psychiatry, 48(2), 290-309. https://doi.org/10.1007/s11013-023-09835-3

Vega Crespo, B., Neira, V. A., Ortíz Segarra, J., Andrade, A., Guerra, G., Ortiz, S., Flores, A., Mora, L., Verhoeven, V., Gama, A., Dias, S., Verberckmoes, B., Vermandere, H., Michelsen, K., & Degomme, O. (2022). Barriers and facilitators to cervical cancer screening among under-screened women in Cuenca, Ecuador: The perspectives of women and health professionals. BMC Public Health, 22(1), 2144. https://doi.org/10.1186/s12889-022-14601-y

Wearn, A., & Shepherd, L. (2024). Determinants of routine cervical screening participation in underserved women: A qualitative systematic review. Psychology & Health, 39(2), 145-170. https://doi.org/10.1080/08870446.2022.2050230

Woldetsadik, A. B., Amhare, A. F., Bitew, S. T., Pei, L., Lei, J., & Han, J. (2020). Socio-demographic characteristics and associated factors influencing cervical cancer screening among women attending in St. Paul’s Teaching and Referral Hospital, Ethiopia. BMC Women’s Health, 20(1), 70. https://doi.org/10.1186/s12905-020-00927-5

Zegeye, A. F., Mekonen, E. G., Gebrehana, D. A., Tekeba, B., & Tamir, T. T. (2025). Spatial variation and multilevel determinants of malaria infection among pregnant women in Sub-Saharan Africa: Using malaria indicator surveys. BMC Infectious Diseases, 25(1), 654. https://doi.org/10.1186/s12879-025-11037-8

Zhang, M., Sit, J. W. H., Chan, D. N. S., Akingbade, O., & Chan, C. W. H. (2022). Educational Interventions to Promote Cervical Cancer Screening among Rural Populations: A Systematic Review. International Journal of Environmental Research and Public Health, 19(11), 6874. https://doi.org/10.3390/ijerph19116874

Published

2026-09-02

How to Cite

Encalada Falconí , J. A., Erosa-De Haro , L. A., Ñaccha Urbano, J. J., Paredes Sandoval, M. M., & Sánchez Navarrete, N. E. (2026). Barriers and factors associated with cervical cancer screening and early diagnosis in women from rural areas: a systematic review. ANNALS SCIENTIFIC EVOLUTION, 5(3), 2628–2647. https://doi.org/10.70577/asce.v5i3.1102

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