Análisis de resultados y protocolo estandarizado para la armonización facial con plasma gel de quinta generación empleando la tecnología CIROI

Bolívar Augusto Merino Montoya; Veronica Paola Jarrin Yerovi; Andrea Johanna Villena Condor; Kimberling Del Carmen Jimenez Diaz; Maijuly Alejandra  Gonzalez Mendez

doi:10.70577/asce.v5i3.974

Authors

Bolívar Augusto Merino Montoya Clínica Internacional de Cirugia Plastica, Medicina Estética y Odontologia Avanzada https://orcid.org/0009-0006-6768-156X
Veronica Paola Jarrin Yerovi Clínica Internacional de Cirugia Plastica, Medicina Estética y Odontologia Avanzada https://orcid.org/0009-0003-1248-0478
Andrea Johanna Villena Condor Clínica Internacional de Cirugia Plastica, Medicina Estética y Odontologia Avanzada https://orcid.org/0009-0008-1630-6481
Kimberling Del Carmen Jimenez Diaz Clínica Internacional de Cirugia Plastica https://orcid.org/0009-0009-0629-9094
Maijuly Alejandra Gonzalez Mendez Clínica Internacional de Cirugia Plastica, Medicina Estética y Odontologia Avanzada https://orcid.org/0009-0004-2755-0085

DOI:

https://doi.org/10.70577/asce.v5i3.974

Keywords:

facial harmonization; plasma gel; autologous plasma; CIROI technology; regenerative medicine; standardized protocol

Abstract

The standardization of protocols in aesthetic regenerative medicine represents a fundamental challenge to ensure the reproducibility and safety of treatments with autologous biological products. This theoretical article critically analyzes the outcomes reported in the scientific literature and establishes a standardized protocol for facial harmonization with fifth-generation plasma gel assisted by CIROI technology. Through a systematic review of available evidence (2019-2025) and analysis of the biophysical foundations of plasma gel, a conceptual model is developed that integrates three interdependent components: the optimal biophysical parameters of plasma gel, the CIROI technological system as a process control device, and the clinical evaluation framework. The analysis demonstrates that the integration of standardization technologies allows for the reduction of interoperator variability by more than 80%, ensures complete process traceability, and achieves patient satisfaction rates exceeding 94%. The proposed protocol specifies critical technical parameters, including centrifugation times, applied G-forces, activation methods, and application techniques. It is concluded that the adoption of technology-assisted standardized protocols constitutes a methodological imperative for evidence-based aesthetic medicine, establishing the foundation for reproducible, safe, and scientifically valid clinical practice.

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