Contribution of Veterinary Medicine to Antimicrobial Resistance Control in Animal Health: A Systematic Review of Scientific Evidence under the One Health Approach (2021-2026)
DOI:
https://doi.org/10.70577/asce.v5i4.1130Keywords:
Animal disease, Epidemiology, Veterinary medicine, Microorganisms, Disease preventionAbstract
The rise of resistant microorganisms compromises the efficacy of treatments, impacts livestock productivity, and facilitates the spread of resistance genes among animals, humans, and the environment. This issue has driven the adoption of the "One Health" approach, which acknowledges the interdependence among these three components and promotes integrated control strategies. The objective was to analyze scientific evidence published between 2021 and 2026 regarding the contribution of veterinary medicine to the control of antimicrobial resistance in animal health, within the framework of the One Health approach. A systematic review was conducted following the PRISMA 2020 guidelines; the search was performed across Scopus, Web of Science, PubMed, ScienceDirect, and SpringerLink, using terms related to antimicrobial resistance, veterinary medicine, animal health, epidemiological surveillance, and One Health. The selection process comprised the phases of identification, screening, eligibility, and inclusion. The studies identified the responsible administration of antimicrobials, biosecurity, vaccination, and epidemiological surveillance as key veterinary strategies. Programs promoting the rational use of antimicrobials demonstrated a reduction in unnecessary antibiotic use when supported by microbiological diagnostics and continuous monitoring. Epidemiological surveillance enabled the detection of resistant microorganisms, such as Escherichia coli, Salmonella spp., Campylobacter spp., and Staphylococcus aureus. It was concluded that veterinary medicine plays a fundamental role in reducing antimicrobial resistance; the results highlight the effectiveness of integrated health management programs and confirm that the "One Health" approach provides the most robust foundation for addressing this issue.
Downloads
References
Ahmed, M. M., Okesanya, O. J., Othman, Z. K., Ibrahim, A. M., Adigun, O. A., Ukoaka, B. M., Abdi, M. I., & Lucero-Prisno, D. E. (2025). Holistic Approaches to Zoonoses: Integrating Public Health, Policy, and One Health in a Dynamic Global Context. Zoonotic Diseases, 5(1), 5. https://doi.org/10.3390/zoonoticdis5010005 DOI: https://doi.org/10.3390/zoonoticdis5010005
Al-Khalaifah, H., Rahman, M. H., Al-Surrayai, T., Al-Dhumair, A., & Al-Hasan, M. (2025). A One-Health Perspective of Antimicrobial Resistance (AMR): Human, Animals and Environmental Health. Life, 15(10), 1598. https://doi.org/10.3390/life15101598 DOI: https://doi.org/10.3390/life15101598
Allerton, F., & Russell, J. (2023). Antimicrobial stewardship in veterinary medicine: A review of online resources. JAC-Antimicrobial Resistance, 5(3), dlad058. https://doi.org/10.1093/jacamr/dlad058 DOI: https://doi.org/10.1093/jacamr/dlad058
Aslam, B., Asghar, R., Muzammil, S., Shafique, M., Siddique, A. B., Khurshid, M., Ijaz, M., Rasool, M. H., Chaudhry, T. H., Aamir, A., & Baloch, Z. (2024). AMR and Sustainable Development Goals: At a crossroads. Globalization and Health, 20(1), 73. https://doi.org/10.1186/s12992-024-01046-8 DOI: https://doi.org/10.1186/s12992-024-01046-8
Ballash, G. A., Parker, E. M., Mollenkopf, D. F., & Wittum, T. E. (2024). The One Health dissemination of antimicrobial resistance occurs in both natural and clinical environments. Journal of the American Veterinary Medical Association, 262(4), 451-458. https://doi.org/10.2460/javma.24.01.0056 DOI: https://doi.org/10.2460/javma.24.01.0056
Bök, P.-B., & Micucci, D. (2024). The future of human and animal digital health platforms. Journal of Reliable Intelligent Environments, 10(3), 245-256. https://doi.org/10.1007/s40860-024-00232-0 DOI: https://doi.org/10.1007/s40860-024-00232-0
Caneschi, A., Bardhi, A., Barbarossa, A., & Zaghini, A. (2023). The Use of Antibiotics and Antimicrobial Resistance in Veterinary Medicine, a Complex Phenomenon: A Narrative Review. Antibiotics, 12(3), 487. https://doi.org/10.3390/antibiotics12030487 DOI: https://doi.org/10.3390/antibiotics12030487
Chakraborty, D., Debnath, F., Giri, S., Saha, S., Pyne, S., Chakraverty, R., Majumdar, A., Deb, A. K., Bhatia, R., & Dutta, S. (2024). Contribution of veterinary sector to antimicrobial resistance in One Health compendium: An insight from available Indian evidence. Frontiers in Veterinary Science, 11, 1411160. https://doi.org/10.3389/fvets.2024.1411160 DOI: https://doi.org/10.3389/fvets.2024.1411160
Da Silva, R. A., Arenas, N. E., Luiza, V. L., Bermudez, J. A. Z., & Clarke, S. E. (2023). Regulations on the Use of Antibiotics in Livestock Production in South America: A Comparative Literature Analysis. Antibiotics, 12(8), 1303. https://doi.org/10.3390/antibiotics12081303 DOI: https://doi.org/10.3390/antibiotics12081303
Dhaka, P., Chantziaras, I., Vijay, D., Bedi, J. S., Makovska, I., Biebaut, E., & Dewulf, J. (2023). Can Improved Farm Biosecurity Reduce the Need for Antimicrobials in Food Animals? A Scoping Review. Antibiotics, 12(5), 893. https://doi.org/10.3390/antibiotics12050893 DOI: https://doi.org/10.3390/antibiotics12050893
Gelalcha, B. D. (2026). Editorial: Antimicrobial resistance in veterinary medicine: epidemiology, economic impact, and mitigation strategies. Frontiers in Veterinary Science, 13, 1783072. https://doi.org/10.3389/fvets.2026.1783072 DOI: https://doi.org/10.3389/fvets.2026.1783072
Gomes, M. P. (2024). The Convergence of Antibiotic Contamination, Resistance, and Climate Dynamics in Freshwater Ecosystems. Water, 16(18), 2606. https://doi.org/10.3390/w16182606 DOI: https://doi.org/10.3390/w16182606
Letten, A. D., Hall, A. R., & Levine, J. M. (2021). Using ecological coexistence theory to understand antibiotic resistance and microbial competition. Nature Ecology & Evolution, 5(4), 431-441. https://doi.org/10.1038/s41559-020-01385-w DOI: https://doi.org/10.1038/s41559-020-01385-w
Miranda, C. (2024). Antimicrobial Usage Monitoring Systems and Stewardship of Antimicrobials in Animal Health. Animals, 14(22), 3325. https://doi.org/10.3390/ani14223325 DOI: https://doi.org/10.3390/ani14223325
More, S. J. (2020). European perspectives on efforts to reduce antimicrobial usage in food animal production. Irish Veterinary Journal, 73(1), 2. https://doi.org/10.1186/s13620-019-0154-4 DOI: https://doi.org/10.1186/s13620-019-0154-4
Motlhalamme, T., Paul, L., & Singh, V. (2024). Environmental Reservoirs, Genomic Epidemiology, and Mobile Genetic Elements. En V. Soni & A. S. Akhade (Eds.), Antimicrobial Resistance: Factors to Findings (pp. 239-273). Springer International Publishing. https://doi.org/10.1007/978-3-031-65986-7_7 DOI: https://doi.org/10.1007/978-3-031-65986-7_7
Mutua, F., Sharma, G., Grace, D., Bandyopadhyay, S., Shome, B., & Lindahl, J. (2020). A review of animal health and drug use practices in India, and their possible link to antimicrobial resistance. Antimicrobial Resistance & Infection Control, 9(1), 103. https://doi.org/10.1186/s13756-020-00760-3 DOI: https://doi.org/10.1186/s13756-020-00760-3
Nardulli, P., Ballini, A., Zamparella, M., & De Vito, D. (2023). The Role of Stakeholders’ Understandings in Emerging Antimicrobial Resistance: A One Health Approach. Microorganisms, 11(11), 2797. https://doi.org/10.3390/microorganisms11112797 DOI: https://doi.org/10.3390/microorganisms11112797
Ohia, C. M. D., Falodun, O. I., Adebudo, L. I., & Bakarey, A. S. (2025). A one health perspective on multidrug-resistant bacterial infections: Integrated approaches for surveillance, policy and innovation. Frontiers in Cellular and Infection Microbiology, 15, 1614232. https://doi.org/10.3389/fcimb.2025.1614232 DOI: https://doi.org/10.3389/fcimb.2025.1614232
Parker, E. M., Ballash, G. A., Mollenkopf, D. F., & Wittum, T. E. (2024). A complex cyclical One Health pathway drives the emergence and dissemination of antimicrobial resistance. American Journal of Veterinary Research, 85(4), ajvr.24.01.0014. https://doi.org/10.2460/ajvr.24.01.0014 DOI: https://doi.org/10.2460/ajvr.24.01.0014
Pereira, V. C., Silva, S. N., Carvalho, V. K. S., Zanghelini, F., & Barreto, J. O. M. (2022). Strategies for the implementation of clinical practice guidelines in public health: An overview of systematic reviews. Health Research Policy and Systems, 20(1), 13. https://doi.org/10.1186/s12961-022-00815-4 DOI: https://doi.org/10.1186/s12961-022-00815-4
Salam, Md. A., Al-Amin, Md. Y., Salam, M. T., Pawar, J. S., Akhter, N., Rabaan, A. A., & Alqumber, M. A. A. (2023). Antimicrobial Resistance: A Growing Serious Threat for Global Public Health. Healthcare, 11(13), 1946. https://doi.org/10.3390/healthcare11131946 DOI: https://doi.org/10.3390/healthcare11131946
Sams-Dodd, J., & Sams-Dodd, F. (2025). The contribution of antimicrobials and antimicrobial resistance to climate change and a possible way to reverse it whilst still offering high quality healthcare—A conceptual analysis. Frontiers in Public Health, 13, 1644086. https://doi.org/10.3389/fpubh.2025.1644086 DOI: https://doi.org/10.3389/fpubh.2025.1644086
Serwecińska, L. (2020). Antimicrobials and Antibiotic-Resistant Bacteria: A Risk to the Environment and to Public Health. Water, 12(12), 3313. https://doi.org/10.3390/w12123313 DOI: https://doi.org/10.3390/w12123313
Vashisht, V., Vashisht, A., Mondal, A. K., Farmaha, J., Alptekin, A., Singh, H., Ahluwalia, P., Srinivas, A., & Kolhe, R. (2023). Genomics for Emerging Pathogen Identification and Monitoring: Prospects and Obstacles. BioMedInformatics, 3(4), 1145-1177. https://doi.org/10.3390/biomedinformatics3040069 DOI: https://doi.org/10.3390/biomedinformatics3040069
Velazquez-Meza, M. E., Galarde-López, M., Carrillo-Quiróz, B., & Alpuche-Aranda, C. M. (2022). Antimicrobial resistance: One Health approach. Veterinary World, 743-749. https://doi.org/10.14202/vetworld.2022.743-749 DOI: https://doi.org/10.14202/vetworld.2022.743-749
Wojnarowski, K., Cholewińska, P., Zhao, D., Pacoń, J., & Bodkowski, R. (2025). Antibiotic Resistance Genes in Food Animal Production: Environmental Implications and One Health Challenges. Environments, 12(11), 427. https://doi.org/10.3390/environments12110427 DOI: https://doi.org/10.3390/environments12110427
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Andrés Patricio Salguero Iza, Carol Lisseth Borja Cuadro, Jean Sebastián Cadena Cando, Stephanie Fernanda Chávez Arrese, David Esteban Puyol Guevara
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Eres libre de:
- Compartir : copiar y redistribuir el material en cualquier medio o formato
- Adaptar : remezclar, transformar y desarrollar el material
- El licenciante no puede revocar estas libertades siempre y cuando usted cumpla con los términos de la licencia.
En los siguientes términos:
- Atribución : Debe otorgar el crédito correspondiente , proporcionar un enlace a la licencia e indicar si se realizaron cambios . Puede hacerlo de cualquier manera razonable, pero no de ninguna manera que sugiera que el licenciante lo respalda a usted o a su uso.
- No comercial : no puede utilizar el material con fines comerciales .
- CompartirIgual — Si remezcla, transforma o construye sobre el material, debe distribuir sus contribuciones bajo la misma licencia que el original.
- Sin restricciones adicionales : no puede aplicar términos legales ni medidas tecnológicas que restrinjan legalmente a otros hacer algo que la licencia permite.
